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The ileocecal valve is observed with inflammatory processes, giving the image of a pseudo tumor, Unusual appereance

This is due to increased small intestinal sodium/glucose cotransporter 1 (SGLT1) expression and subsequent GLP-1 release following intestinal glucose infusion, which are mediated by metformin-induced alterations in the small intestinal microbiota 131

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These surprising benefits appear to be due to the potent anti-inflammatory and anti-fibrotic effects of semaglutide [1] on the whole body, with systemic reductions in oxidative stress and inflammatory cytokines [2] (the signalling molecules the body makes)