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It would also be pertinent to add laboratory assays that allow putting the results in the larger context of cellular senescence, which seems to be disturbed in several disorders where fatigue has been associated with mitochondrial dysfunction

In non-mature populations, an increase in linear growth rates was reported aligning with these peptides proposed role in supporting developmental growth pathways

The suggested dithiol mechanism was based on experiments at a single substrate concentration that required more than 8 h for redox equilibration in the presence of 0.5 M glutaredoxin with or without 1 M GSH

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