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It's a little-known fact that inulin and oligofructose from chicory fiber are low energy-dense ingredients conveying only 2 kcal/ gram in a food product compared to 4 kcal/gram for sugar or 9/kcal for fat
There have also been rare cases of kidney failure and brain swelling linked to the use of melanotans
In animal research, increasing plasma adiponectin levels through pharmacological or genetic means has shown to alleviate obesity-induced endothelial dysfunction, hypertension, atherosclerosis, myocardial infarction, and diabetic cardiomyopathy
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