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This is because GHK-Cu itself works in picogram quantities

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Oral supplements take an obstacle course

B12 is known to play a key role in numerous functions in the body, including (but not limited to): DNA and red blood cell formation Maintaining a healthy metabolism and digestion Synthesis of neurotransmitters and hormones Energy production Nerve cell health Gene and enzyme regulation Athletic prep or recovery Vitamin B12 shots may also help reduce the risk of the following conditions: heart disease, neurological function, stroke, cognitive functions such as thinking and memory, problems with fertility, and neural tube defects in children born to parents with a vitamin B12 deficiency