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Efimosfermin Efimosfermin is a long-acting genetically engineered variant of human FGF-21, stabilized by amino acid substitutions, and fused to the N-terminus of the human IgG Fc domain (Fc-FGF-21)

The STEP-5 trial extended this to 104 weeks and confirmed durable weight loss of 15.2% with the full dose 3

Despite the increase in weight management approaches, the pandemic of obesity is still rising

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