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The gut lining is a crucial aspect of our immune system as it acts as a barrier to bacteria and other toxins, preventing them from crossing from the gut
(Staud points out that a more acidic mileu in the muscles possibly produced by low oxygen conditions in FM primes the pain receptors in the muscles to act up.) EEG studies suggest the muscles in FM have trouble relaxing, causing them to stay in a more contracted state a state that can be associated with hypoxia and causes increased pain sensitivity
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