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Biologic therapies effectively target specific inflammatory mediators, but do not directly address metabolic dysfunction or oxidative stress, both of which contribute to HS severity

Because these two approaches work in different ways, we recommend making this shift under the guidance of a licensed healthcare professional. There are 2 ways to transition: Immediate switch Gradual taper If switching immediately, you may notice a return of hunger or cravings, especially if lifestyle habits (like nutrition and movement) werent established during your time on synthetic GLP-1

Flint SW, Vzquez-Velzquez V, Le Brocq S, Brown A

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