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Chemically stable in gastric juice (originally isolated from gastric juice), allowing it to retain biological activity through the GI tract
Long-term use has become much easier with the latest oral version of these medicines, which does not require an empty stomach
Semaglutide creates the caloric deficit through appetite suppression
The metabolic benefits tended to revert back towards baseline, but some, like insulin, triglycerides, and improvements in quality of life, were still significantly better
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