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Experimental and human metabolic literature demonstrates that GH promotes fatty acid mobilization, shifts substrate preference toward fat oxidation, and alters carbohydrate-lipid partitioning during fasting and metabolic stress states, making GH secretagogue systems useful tools for investigating adipose tissue signaling, fuel selection, and the endocrine regulation of energy metabolism [8]

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What the evidence is preclinical actually means for a reader Preclinical means the findings come from cell cultures and animal models, not from controlled human trials

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