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The last option maintains therapeutic continuity when the commercial product is temporarily inaccessible

Attached THP-1 cells were stimulated with 100 ng ml 1 lipopolysaccharide (Sigma) for 3 h and treated with DMSO, GSTO1 inhibitors or Glyburide (Enzo Life sciences) in serum-free media for 1.5 h followed by addition of 5 mM ATP (Sigma) for 30 min

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Zatorski H, Saaga M, Zieliska M et al (2015) Experimental colitis in mice is attenuated by topical administration of chlorogenic acid