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Before taking, speak with your doctor if you are allergic to vitamin b12, have a genetic condition called optic atrophy, have blood in your urine, polycythemia, an ongoing infection, low iron or folate levels, are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed
Summary: Excessive vitamin B12 intake rarely causes toxicity, but very high levels from supplements or injections may be associated with skin reactions such as acne-like eruptions, though serious adverse effects remain exceptionally uncommon
For oral administration, take on an empty stomach, preferably first thing in the morning at least 30 minutes before eating
PMID 30845641
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