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In fast-moving pharma markets, perception often changes faster than market share.
The chemical structure of AIBA is shown below: Compare the structures of AIBA (found in semaglutide) and the amino acid in position 2 of GLP-1 (residue (iii) in Figure 2)
The other incretin hormone, glucose-dependent insulinotropic polypeptide (GIP), generally shows impaired insulinotropic activity and limited glucose-lowering effectiveness in type 2 diabetes (T2D)
Diabetologia 36 , 741744 (1993)
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