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Food and Drug Administration (FDA) approval for T2DM in adults and chronic weight management in adults with obesity ( Across the phase 3 SURPASS program, tirzepatide consistently demonstrated clinically relevant effects on glycemic control, with dose-dependent reductions in body weight in patients with T2DM
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Short-term clinical trials have sometimes reported minimal or no significant shifts in gut microbiota despite marked metabolic improvements
[3] GHRP-6 became the prototype
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