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This is especially common in recurring therapies, where documentation does not reflect changes in the patient's condition
The mutation of GIPR Glu 354 to Gln increases GIP affinity, enhances the agonist residence time by 25%, increases cAMP activity, and facilitates the rate of internalization by 2.12.3-fold
Sequential Administration Studies: Another valid approach is to study the effects of one peptide, followed by a proper washout period, and then the administration of the second peptide in the same cohort
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