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As glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and newer dual- or tri-receptor agonists (incretin mimetics) redefine metabolic health management, oncology clinicians increasingly face questions about their use during and after active cancer treatment

Plasma half-life studies in research models consistently show 4560 minute elimination half-lives, translating to 45 half-lives (roughly 45 hours) for 94% clearance and 67 half-lives (68 hours) for 99% clearance

Also, for older folks, they really cannot afford to lose that muscle mass because risk of falls, fractures, etc, go up