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1 Introduction Lenvatinib is a small-molecule tyrosine kinase inhibitor (TKI) that targets multiple receptors, including vascular endothelial growth factor receptors (VEGFRs) 13, fibroblast growth factor receptors (FGFRs) 14, and platelet-derived growth factor receptor (PDGFR) and (Matsui et al., 2008)

In the body, EGF binds to ErbB1 receptors on keratinocyte surfaces and triggers a tyrosine kinase cascade that accelerates epidermal cell proliferation, migration, and differentiation

"Without addressing the underlying causes [of obesity ] whether through lifestyle changes, behavioral interventions, or personalized treatment weight loss may not be sustainable, explains Andres Acosta, MD, PhD , associate professor of medicine at Mayo Clinic