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Similarly, the LEADER trial with liraglutide showed a numerically higher, though non-significant, rate of diabetic retinopathy events compared to placebo (HR, 1.15
In other words, these medications dont specifically cause muscle mass loss
Never try to catch up by taking two doses at once
This creates a unique metabolic dance that the body needs time to adjust to, which is why the retatrutide dose schedule uses a gradual titration over many weeks
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