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Although the PPP operates in all cells, with high levels of expression in the above indicated tissues, the highest levels of PPP enzymes (in particular glucose 6-phosphate dehydrogenase) are found in neutrophils and macrophages
95 In NSCLC, resistance to MET inhibitors can arise from acquired mutations within the MET kinase domain
It may be related to the dose of the toxic drug used or the period of study observation.However, most of the current research results support the antioxidant stress effect of GPX1, so GPX1 is an important antioxidant in mammals
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