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Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53
Knowing how the molecule works, what its approved uses are, and which symptoms warrant a call back to a provider turns a quick online consultation into a genuinely informed one
If side effects persist and remain intolerable despite extended up-titration, a lower maintenance dose may be considered to support adherence and reduce the risk of treatment discontinuation [66]
Regular Follow-Up Is Important Routine provider visits help evaluate progress, discuss expectations, and determine whether ongoing treatment remains appropriate
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