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If injection site reactions are driving you to consider a switch, have an honest conversation with your provider about the available options and their relative effectiveness for your specific situation

In the pivotal SURMOUNT-1 trial involving adults without diabetes, participants receiving the highest dose (15 mg) lost an average of 20.9% of their body weight over 72 weeks, compared to 3.1% with placebo

Outside the CNS low level HRH3 expression has been found in the gastrointestinal and cardiovascular systems and in bronchial cells of the lungs

The FDA has not reviewed this product for safety or effectiveness