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It is easy to handle and practical for routine laboratory applications where reproducible preparation steps are required
Notably, the PNA model mimics a lean phenotype with subtle metabolic alterations and may phenocopy the human phenotype B of PCOS 45 , characterized by hyperandrogenism and oligo-anovulation, with cycle irregularities
This means the medication's appetite-suppressing effects gradually weaken, even at the same dose
The ampules are suitable for oral, intravenous, intramuscular and subcutaneous use
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