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The focus is GLP-1s because thats whats really driving much of this, Hertig said
Peptide degradation produces fragments and aggregates that may trigger immune responses
Regarding clinical outcomes, there is evidence, derived from observational and case-control studies, suggesting that in patients with T2DM and advanced fibrosis or cirrhosis associated with MASLD, metformin may improve transplant-free survival without affecting the risk of hepatic decompensation, in addition to reducing the risk of hepatocellular carcinoma and extrahepatic neoplasms
While both Rybelsus (semaglutide pill) and Ozempic (semaglutide injection) are used in type-2 diabetes patients to improve glycemic control, these two medications are not the same, meaning, they are not interchangeable
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