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Natural GLP-1 is easily degraded by enzymes with a short half-life of only 2-5 minutes, making it unavailable for direct therapeutic use
Meal composition also affects speed: eating large amounts of simple carbohydrates or high-fat foods before peak drug levels blunts appetite suppression compared to protein-forward meals
Alcohol, on the other hand, can drop blood sugar temporarily before causing it to rise later
This is the most precise option for small doses
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