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The GCGR component is specifically hypothesised to contribute via cyclic AMP-mediated beta-oxidation pathways in hepatocytes, though this mechanistic attribution requires further controlled validation [VERIFY]
Researchers want to know where retatrutide fits in the landscape of metabolic peptides, and the data makes the positioning clear
Hum Mol Genet 9(19):28372844 Ducker GS, Rabinowitz JD (2017) One-carbon metabolism in health and disease
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