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The Key Problem Fair-skinned people produce mostly pheomelanin and very little eumelanin, even when they try to tan

GIP Receptor : Activating the GIP receptor further enhances insulin release and may have additional effects on fat metabolism

Data was acquired using Thermo Xcalibur 4.0 Software (Thermo Scientific, Waltham, MA USA) MS data processing and analysis were made using Skyline software (V20, MacCoss Lab, University of Washington, Seattle, WA)

For the analyses of this estimand, missing values (unobserved due to patient loss to follow-up or other reasons) were assumed to be missing at random and were handled by multiple imputation using observed data in the placebo group