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preclinically reported to drive angiogenesis and tissue repair
HUBERMAN: It's the fact that even though we know a lot about the human body and the various hormones and neuromodulators like dopamine, serotonin, et cetera, that are made, this landscape of peptides is an enormous one
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The study confirmed FOXO4-DRI was effective across senescent cells generated by different methods (irradiation, doxorubicin, and replication stress), and documented that pre-treatment with FOXO4-DRI attenuated the dedifferentiation of chondrocytes during in vitro expansion establishing it as a valuable tool for research into senescent cell biology in cartilage and musculoskeletal models
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