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For patients planning pregnancy, semaglutide should be discontinued at least 2 months before a planned pregnancy due to its long half-life
The peptide is particularly sensitive to heat, and exposure to temperatures above normal refrigeration accelerates degradation significantly
Twelve samples preserved in 4% paraformaldehyde undergo ethanol dehydration through graded concentrations (85% for 2 h, 95% for 2 h, followed by 100% for 1 h each) before being cleared in xylene and embedded in paraffin
The GLP-1 group included people taking medications such as semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda), though the records did not specify exactly which drug each person used
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