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GSH inhibits PSC activation induced by high glucose via the ROS/TGF/SMAD pathway in vitro The above results indicated an increase in pancreatic fibrosis in rats treated with LOsG, which was accompanied by an increase in ROS/TGF/SMAD signalling, and PSC proliferation and activation, which were all prevented by GSH
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The GST tag enhances the solubility of fusion proteins expressed in Escherichia coli and is used to purify fusion proteins due to its ability to bind to immobilized glutathione (GSH) on agarose beads 1
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