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Phase 2 Efficacy and Safety: The Core Dataset The key Phase 2 trial (NCT04881706) randomized 338 adults with obesity or overweight plus at least one comorbidity to placebo or one of six retatrutide dose levels (1 mg, 4 mg escalated from different starting doses, 8 mg, or 12 mg) for 48 weeks [1]
Kiani CS, Hunt RW
Methylglyoxal and other -dicarbonyls are also involved in ROS generation
The good news: It's typically temporary
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