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Disruption of this central regulatory system, including alterations in TRH, CRH, and GnRH secretion, provides a mechanistic explanation for the broader physiological consequences of mycotoxin exposure (177), such as growth retardation, reproductive disorders, and appetite dysregulation (178180)

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PMCID: PMC8373505 Pivonello C, Negri M, Patalano R, Amatrudo F, Mont T, Liccardi A, Graziadio C, Muscogiuri G, Pivonello R, Colao A (2022) The role of melatonin in the molecular mechanisms underlying metaflammation and infections in obesity: A narrative review

These toxins are highly inflammatory to the immune system and trigger intense immune responses