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Two SGLT2 inhibitors, Farxiga (dapagliflozin) and Jardiance (empagliflozin), have emerged as powerful treatment options that go beyond blood sugar control
SIRT1 function is also modulated through protein-protein interactions: DBC1 inhibits SIRT1 activity via complex formation, 30,49 whereas AROS and SENP1 interact with SIRT1 to enhance its activity, expanding the spectrum of functional regulation
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References Fatima MT, Ahmed I, Fakhro KA, Akil ASA
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