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Melanin nanoparticles alleviate sepsis-induced myocardial injury by suppressing ferroptosis and inflammation
Bilateral injections of AAV vectors encoding for stimulatory (AAV8-hSyn-DIO-hM3Dq-mCherry, Addgene, 44361-AAV8) or inhibitory (AAV8-hSyn-dF-HA-KORD-IRES-mCitrine, Addgene, 65417-AAV8) Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) were then performed in the OB (A/P: +4.8 mm from bregma, M/L: 1 mm and D/V: 1.7 mm from brain surface) at a rate of 0.125 L/min for 4 min, on Glp1r -Cre RD and WD mice
Like other peptides, it can provide a novel remedy to health issues
