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Between these two, metformin is our first-line preference as it helps not only with antipsychotic-related weight gain but also with the metabolic side effects of antipsychotics (insulin resistance, fasting glucose, triglycerides, and hyperprolactinemia), earning it a recommendation from the APA for this purpose
It can help with choosing the best peptide for weight loss
use at different times (e.g., AM vs PM)
However, it can be influenced by age and education, and repeated administration can lead to practice-related improvements that complicate the assessment [89]
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