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Following the ingestion of D-allulose, body fat percentage and body fat mass significantly declined.* Compared to the sucralose group, the group given the higher dose of D-allulose had a significant decrease in not only body mass index, but also total abdominal and subcutaneous fat areas, as measured by CT scans.* The FDA considers D-allulose to be GRAS (generally recognized as safe) with an intake of less than 0.5 to 0.6 g per kg of body weight per day

Discuss with your healthcare provider if these symptoms persist

these changes are thought to be related to changes in cravings, hunger and fullness (Mozafarriun et al 2025)

498,499,500 Additionally, pioglitazone hydrochloride is being studied for its effects on brain tumors, RA, MS, PD, and certain cancers