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In a multicenter, randomized, placebo-controlled dose-finding trial, cagrilintide at doses ranging from 0.3 to 4.5 mg weekly produced dose-dependent weight reductions, with the 4.5 mg dose achieving approximately 10.8% weight loss at 26 weeks compared to 3.0% with placebo
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It is more likely to occur in those patients receiving too much of the medicine but can occur with small doses as well
Beyond purity and identity, a thorough COA reports a bacterial endotoxin result from the Limulus Amebocyte Lysate (LAL) assay, ideally in line with USP
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