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The FDA found no clinical studies or publicly available human exposure data for administered MOTS-c, no adequate toxicology, uncertain characterisation and unresolved immunogenicity.[6] The same caution applies to a large range of other non-GLP-1-related peptides that are promoted well beyond the supporting human evidence and in the absence of adequate safety data.[8] Unapproved peptides are not included in the Australian Register of Therapeutic Goods and have not been evaluated by the TGA for safety, quality or effectiveness

Stress management does not need to be complicated