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Um, it may, I mean, there is, there is data suggesting that some of the proteinopathy that occurs in the brain in Parkinsonism might begin in the gut and then find a way to travel up the vagus nerve to the brain

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Ciobanu DA, Ganea C, Marcu RO et al (2020) JAK/STAT pathway in pathology of rheumatoid arthritis (review)

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