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The ability of NRF2 to regulate xCT coupled with the decline of NRF2 with age 178 might account for the increased levels of plasma cystine seen with increasing age
Examples include inhibitors of IL-1, IL-6, or components of the NF-B pathway
While lipid- and DHA-conjugated forms tend to outperform free AST in cognitive improvement and plaque reduction, no standardized regimen exists, making comparisons across studies difficult
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