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(1) This growing population faces elevated risks of developing metabolic complications, notably type 2 diabetes, and is increasingly in need of effective and sustainable therapeutic strategies

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Monotreme GLP-1 peptides bind with lower affinity to the GLP-1 receptor than human GLP-1 We then asked how changes in pGLP-1 and eGLP-1 affect binding and activation of the GLP-1 receptor (GLP-1R)

To view or add a comment, sign in I definitely agree with the following statement discussing the next phase of potentially making precision psychiatry a reality The proposal is straightforward: Move toward biomarker-driven patient stratification Design more flexible, biology-informed clinical trials Align regulatory approaches with what already works in oncology and dementia Dementia offers a useful reference point