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Organ and tissue growth concerns Because IGF-1 signaling affects cellular growth and proliferation throughout the body and not exclusively in skeletal muscle, there is concern that long-term use of IGF-1 could result in increased growth of other tissues/organs in the body

So yes, symptoms can get worse before they get better

A recent small study of healthy older adults given glyNAC, a supplement that increases glutathione levels, showed lower oxidative stress and inflammation after 24 weeks of treatment (10)

And, heres a tip: If youre experiencing deficiency symptoms, the best test is a urine MMA not serum B12 level)