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Now, hundreds of thousands of patients are stuck navigating uncharted waters as companies they entrusted with their health pursue strategies that may disrupt their care or present risks

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This distinction leads to key differences in development and manufacturing: Peptide-based GLP-1 drugs require complex synthesis and formulation processes Small-molecule GLP-1 drugs are generally easier to manufacture at scale Oral bioavailability and stability present different technical challenges These differences highlight the contrasting development paths between peptide-based and small-molecule GLP-1 therapies, which continue to shape industry competition

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