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Hohe Konzentrationen finden sich in der Leber, Lunge, Niere, den Schleimhuten des Magen-Darm-Trakts und im Gehirn
At 10 mM, NAC feeding significantly protected against APAP induced mortality relative to vehicle control (Fig
of going to the beach and not taking my sarong off to hide my legs
The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting
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