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Moreover, preclinical and early phase clinical trials have confirmed the therapeutic potential of entero-pancreatic hormone combinations in obesity and/or metabolic complications such as T2D [33]
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If clinical trials continue to show the current results, retatrutide will likely become the most effective single medication for weight loss once approved
GLP-1RAs not only have the potential to treat the above-mentioned diseases but also ameliorate the co-morbidities simultaneously, which is important for patients with autoimmune/autoinflammatory diseases combined with metabolic diseases
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