tirzepatide pregnancy discontinue how long before conception label TLDR on GLP-1 receptor agonists (ozempic, wegovy, monjauro, zepbound etc etc) animal studies suggest a possible association with birth defects, low fetal weight, and miscarriage but human data (which GLP-1s are everywhere, and so

However, the data suggest that for most individuals, semaglutide is well-tolerated, and the benefits of weight loss and lower blood sugar levels often outweigh any side effects people experience

Published literature on the association between gastroparesis and any GLP-1RA, not just Ozempic, should have alerted manufacturers to the need for warnings about this risk to patients and prescribing physicians

From needles to pills: oral GLP-1 therapy enters the obesity arena

Citation33 Actinobacteriota-derived acetate also may enhance insulin sensitivity via G protein-coupled receptor (GPCR) signaling in adipose tissue and the liver