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It doesn't happen instantaneously at a specific date it's a gradual degradation that accumulates over time with exposure to heat, moisture, light, and freeze-thaw cycles

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BPC-157: Comprehensive Clinical Profile and Molecular Analysis Introduction: The Gastric Pentadecapeptide BPC-157 (Body Protection Compound-157) represents a stable gastric pentadecapeptide consisting of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

USP Controlled Room Temperature also permits brief excursions between 15 and 30C, so a slightly warm or cool room is not a problem