Search terms included GLP-1 receptor agonist, diabetic retinopathy, glaucoma, age-related macular degeneration, ocular disease, and neuroprotection. The search included preclinical studies, large-scale retrospective cohort studies, and post-hoc analyses of major cardiovascular outcome trials (CVOTs)
GLP-1 medications work by stimulating specific receptors on pancreatic beta cells to regulate blood sugar and appetite
Reduced incidences and delays to onset of diabetes-related complications associated with semaglutide-based treatment amounted to clinical benefits and greater expected quality of life for patients over the modelled time horizon
It helps reduce inflammation, speeds up the repair of muscles, tendons, and ligaments, and promotes faster recovery from injuries