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Rotating Injection Sites Rotating injection sites is essential to prevent irritation, discomfort, or changes in the skin such as lipohypertrophy (a buildup of fat under the skin)
Indeed, the constitutively active Rab7 (Q67L) mutant which is unable to undergo Rab7 GTP hydrolysis leads to a higher percentage of lysosomes forming stable contacts and an extended duration of contact tetherings than wild-type Rab7 (Wong et al., 2018)
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There are some common side effects with the injections, but theyre not serious and typically resolve without intervention
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