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In a prospective cohort study of 36 patients with albuminuria who were initiated on sitagliptin 50 mg daily, patients experienced a significant change in both systolic and diastolic BP that was apparent after 6 months (baseline systolic BP 140 +/ 18 mmHg dropped to 129 +/ 17 mmHg and baseline diastolic BP 77 +/ 10 mmHg fell to 73 +/ 7 mmHg
Similarly, the DIADEM trial showed 60% remission rates in younger individuals (aged 1850 years) with early intervention [80], proving that reversibility is achievable across ages
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Coverage depends entirely on your individual plans formulary, whether its prescribed for an FDA-approved indication (primarily type 2 diabetes and cardiovascular risk reduction, not typically off-label for weight loss alone), and if it meets any prior authorization or step therapy requirements set by your insurer
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