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Effects of melatonin supplementation on hormonal, inflammatory, genetic, and oxidative stress parameters in women with polycystic ovary syndrome

Temporary fatigue or mild flulike symptoms sometimes occur during the first 1-2 weeks as the body adjusts to enhanced detoxification activity

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Similarly, decreased lactylation of malate dehydrogenase 2 at K241, coupled with reduced lactate production, leads to elevated levels of GSH and GPX4, thereby alleviating ferroptosis and improving mitochondrial function in myocardial IRI (120)