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What seems to matter most: What your appetite was like before you started How long you were on treatment Your dose Whether you built healthy habits you can maintain without the medication Should you taper off a GLP-1 or stop cold turkey
Patients should consult a qualified clinician before restarting, especially if other health conditions or medications have changed
Recognising these additional features is important for prompt diagnosis and treatment, particularly as some neurological complications may become irreversible if left untreated for extended periods
These treatment patterns need to change. Meanwhile, more data on tirzepatides impact on a broad five-component cardiovascular end point including all-cause mortality are expected from the placebo-controlled SURMOUNT-MMO outcome trial in 15,000 patients with obesity but no diabetes
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